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How MRNA Vaccination Was Invented

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The True Story Of How MRNA Vaccination Was Invented

Dr. Robert Malone is the inventor of mRNA vaccines (and DNA vaccines). He also discovered lipid mediated and naked RNA transfection technologies.

It all started when he was at the Salk Institute in 1987 and 1988. There, he pioneered in-vitro RNA transfection and also in-vivo RNA transfection (in frog embryos, as well as mice).

This resulted in his seminal paper: Cationic liposome-mediated RNA transfection RW Malone, PL Felgner, IM Verma. Proceedings of the National Academy of Sciences (PNAS) 86 (16), 6077-6081

His filed patent and disclosures from the Salk included in-vivo RNA transfection and also methods for mRNA stabilization – now being claimed as invented by others. These are available for review.

His research was continued at Vical in 1989, where the first in-vivo mammalian rat experiments were designed by him.

The mRNA, constructs, reagents were developed at the Salk institute and at Vical by Dr. Malone, this included dosing amounts for the in-vivo experiments. RNA and DNA were sent to Dr. Jon Wolff via Fedex.

Dr.Wolff at the University of Wisconsin injected mice and rats. The initial patent disclosures for RNA and DNA vaccination were written by Dr. Malone in 1988-1989. Dr. Malone was also an inventor of DNA vaccines in 1988 and 1989.

This body of work resulted in over 10 patents and numerous publications, yielding about 7000 citations for this work. The paper was the first showing data for DNA and RNA side by side for in-vivo (the first paper for in-vivo DNA):

Direct gene transfer into mouse muscle in vivo. Wolff JA, Malone RW, et al. Science. 1990;247(4949 Pt 1):1465-8. Cited in 4,750 articles, is the result of that work.

In 1989, research was performed that gave rise to the 10+ groundbreaking patents on mRNA vaccination, all with a priority date of March 3, 1989.

This is the same priority date as the Salk Patent application, showing that the two institutions were working together (without Robert’s knowledge).

These patents are the first published research on mRNA vaccination. The titles and links to the patents are listed in the documents below.

These patents have proof of principle experiments on mRNA vaccines – that clearly document that the invention worked and that these are the first experiments showing this.

Vical was to license the Salk Technology.

Instead, they hired Robert’s thesis advisor from the Salk and soon after, the Salk dropped the patent and Vical never pursued a license from the Salk.

Due to an employee contract with Vical, this stopped Robert from working in the field commercially for a decade. Vical claimed all the Salk research happened at Vical and sent a cease and desist letter.

Dr. Malone carried on his research into mRNA vaccination during the 1990s, culminating in a mucosal patent that was issued in 2000. He also helped revolutionized the field of cationic liposomes for the use in RNA vaccinations.

This work was so far ahead of its time, that only now is the world turning to mucosal mRNA vaccination as a method of immunization. For a listing of some of his work, see the publications at the end of this page.

Scientifically trained at UC Davis, UC San Diego, and at the Salk Institute Molecular Biology and Virology laboratories, Dr. Malone received his medical training at Northwestern University (MD) and Harvard University Medical School (Clinical Research Post Graduate), and in Pathology at UC Davis.

He has almost 100 peer-reviewed publications and has been an invited speaker at about 50 conferences.

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15 COMMENTS

    • She did not account for the beer fridges.

      Don’t be like Mega Pie
      Don’t forget the beer fridges in your calculation !

      Beer fridges can throw the numbers.

      Friday 5 pm announcement.
      There will be state registration of beer fridges.
      If the ships dont get through with the Indonesian coal, Govt will consider a beer fridge buy-back to ‘lower the load’.

      From October 2021 you will need a beer fridge passport to purchase or acquire a beer fridge.
      Illegal hoarders and holders of beer fridge’s will face a fine plus imprisonment.

      7

      0

      • Friday 5 pm announcement.
        There will be state registration of pie warmers.
        If the ships don’t get through with the Indonesian coal, Govt will consider a pie warmer buy-back to ‘lower the load’.

        From October 2021 you will need a pie warmer passport to purchase or acquire a pie warmer.
        Illegal hoarders and holders of pie warmers will face a fine plus imprisonment.
        As usual, the elites will be immune to all these requirements.

        5

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  1. mRNA, Maybe not financially, but morally you really wouldn’t want to end up in history with your name anywhere near this technology.
    It is shaping up as one of the greatest contributor to death and co morbidity ever delivered to mankind, supposedly in a legal way.

    10

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    • Unfortunately, Dr Robert Malone did not have control of his work and how it was used. However it does mean he is an expert in this field. And if he says it is broken and dangerous, it is broken and dangerous.

      Discovering something, but not acting upon it, and having someone else use your work for to create chaos and riches, are two totally different things. Should Ernest Rutherford roll over in his grave for all the victims of nuclear weapons? I don’t think so.

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      • Absolutely correct Dylan.
        There was some similar “game playing” or intellectual property theft involving a certain Dr Tony Fauci . He stole original research, related to HIV, from Dr Judy Mikovitis ..twice.

        4

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        • It reminds me of a true story.

          A young art student, in order to test his skills, rightly or wrongly, decided to see how well he could replicate some NZ bank notes, presumably for an art project. It was an innocent project, and never intended to be spent. He left them out drying.

          Some time later, while while student was out working, an elder member of the family about to leave for the pub, saw the money and decided to “borrow it” expenses, and pocketed the now dry cash. The cash was accepted in the pub and nothing ever happened from it, but it could have easily resulted in counterfeiting charges.

          Sometimes, those who create something, never intend it to be used, or it is not able to be used.

          4

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      • ‘all the victims of nuclear weapons’

        It has only ever been Japanese people.
        No-one else.
        From USA bombs.
        For all the noise, distraction, misinformation, and fear mongering.

        Now where I have I recently heard ….noise, distraction, misinformation, and fear mongering

        1

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        • Not entirely true howitis…
          -Depleted uranium warheads
          -Mini Nukes used in various ‘disasters’. Where supposedly normal weapons or accidents were involved but disaster sites measured very high levels of radiation.
          -Over 1000 nuclear weapons tests in the very upper atmosphere by the USA and USSR since the 1960’s. Not of lately though. Many of which ripped through the ozone layer, tearing it like a maiden’s nighty, and causing weather disturbances and localised heating, which gave the impression of climate change.

          3

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  2. The gent in the picture is a dead ringer for James Brolin

    https://www.google.com/search?q=James+Brolin&tbm=isch&chips=q:james+brolin,g_1:actor:_58Snl3rK_c%3D&rlz=1C1CHBF_enNZ836NZ836&hl=en-US&sa=X&ved=2ahUKEwj74vXc26zyAhXBsUsFHeiwAf8Q4lYoBnoECAEQHA&biw=1349&bih=625#imgrc=t0Y2GkHwu5R6OM

    You really have to wonder, since he married Streisand, does the Meatloaf song play over and over in his head:-
    ..’and now I’m praying for the end of time ‘

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