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What’s All The Buzz About Quercetin?

By Brian C. Joondeph, M.D.


Quercetin has been in the news lately, particularly as one of many potential therapeutics that might have some benefit in the prevention or treatment of COVID infection. Is there anything to this?

Big media and the medical establishment are quick to pounce on any “unapproved” potential therapeutics that haven’t gone through large prospective randomized clinical trials and don’t have the seal of FDA approval. Even FDA approval is not enough if the medications are being used off-label, as in the case of hydroxychloroquine or ivermectin.  Decades ago, both were deemed safe and effective by the FDA and approved for human use, although not for COVID or similar viral infections as COVID didn’t even exist when the FDA approved these medications.

Today there is a peculiar hostility toward these medications, both of which are on the list of the World Health Organization’s essential medicines. A Fox News host told viewers that hydroxychloroquine “will kill you” and the FDA told its Twitter followers that ivermectin is for horses and cows and to stop using it. This must have been shocking news to millions around the world who take these medications, some for many years, in the U.S. prescribed by a physician, and elsewhere in the world readily available over the counter.

I am not advocating for or against these drugs, instead referring interested readers to other sources of information on the science and potential benefits of these medications in our fight against COVID. Quercetin appears to be the third in this line of potential therapeutics, not yet being called horse paste but, if history is a guide, it may soon be maligned as dog and cat medicine, something that can also be said for many drugs taken by humans but also used in animals.

What is quercetin? It’s described as “a pigment” which may lead CNN or Fox News to equate its use to drinking paint. Technically it is a flavonoid, “a group of plant metabolites thought to provide health benefits through cell signaling pathways and antioxidant effects. These molecules are found in a variety of fruits and vegetables.”

These compounds have several health benefits including reducing the risk of heart disease, cancer, and degenerative brain disorders through anti-inflammatory effects as a free radical scavenger. While present in fruits, vegetables, and green tea, it is also available as a non-prescription supplement in capsule or powder form.


Quercetin, like hydroxychloroquine and ivermectin, is a zinc ionophore, facilitating the entry of zinc into cells where it interferes with viral replication, potentially suppressing COVID infection.

Could quercetin be of benefit against COVID, or for that matter, the common cold or the flu? As are always told to “follow the science”, what does science say?

A 2012 paper published in Antiviral Research found that quercetin inhibits rhinovirus (common cold) replication both in vitro and in vivo, meaning in the laboratory and in humans. Another 2016 paper in Viruses noted that quercetin inhibited influenza A (seasonal flu) virus entry into cells. Is quercetin a cure or panacea? Certainly not as we have no cure for these viral infections. But following the science leads to the conclusion that it helps. But what about for COVID?

Following the science, rather than the FDA Twitter feed, suggests that quercetin may be of benefit in COVID. A 2021 paper in the International Journal of General Medicine, a prospective, randomized, controlled clinical trial of 152 early-stage COVID patients, the type of study always demanded by Dr. Anthony Fauci and the medical smart set, concluded, “Quercetin is a safe agent and in combination with standard care, when used in the early stage of viral infection, could aid in improving the early symptoms and help in preventing the severity of COVID-19 disease.”

The same group published in the same journal, also in 2021, a smaller similarly designed clinical study concluding, “Quercetin statistically shortens the timing of molecular test conversion from positive to negative, reducing at the same time symptoms severity and negative predictors of COVID-19.”

I must add the standard and necessary disclaimer that I am not anti-vaccine, having been personally vaccinated in 2020. Nor am I offering medical advice. Any medical treatment, including over-the-counter supplements, should be used only after due diligence and/or in consultation with one’s own physician. Sorry, but this is a necessary paragraph.

Four scientific papers, yet crickets from the media. The last two studies show quercetin reduced “symptom severity,” meaning the difference between a cold one can recover from at home versus a trip to the hospital or worse, that one might not recover from. Isn’t this what vaccines do?

The CDC tells us that the COVID vaccines “help keep you from getting seriously ill.” This is what the quercetin studies found as well. One approach is mandated, a vaccine, a medical intervention, with loss of job, travel, and freedom if you refuse. The other approach, a supplement taken once or twice a day, something readily available at any grocery or health food store, one of myriad supplements on the shelf, is ignored.

What can’t be ignored is that after a year and a half, COVID is still with us. In my home state of Colorado, 78 percent of adults and 63 percent of the 12-and-over population currently have had at least one vaccine dose. Yet at the same time the Denver Post ran this headline, words I haven’t seen since the spring of 2020, “Colorado could stop elective surgeries, activate crisis standards next week if COVID numbers don’t improve.”

It’s clear that COVID is not over, and in some locations is far from it. There will be variants and surges. Meanwhile, the world is upside down from long lockdowns, business closures, masks, quarantines, testing, vaccinations, and finger-wagging from the media who always promise that if we do what they say all will be good. Yet it is not.

We are long past all-hands-on-deck time. Anything we can throw at the COVID beast that might have some benefit, including quercetin and other previously mentioned therapeutics, should be heralded, not maligned, or ignored. Instead, we are on a one-speed bike, pedaling into a strong headwind, guided by the corporate media, big pharma, and a politically motivated medical establishment, making only slow progress, seemingly oblivious to the costs in human suffering.

This leads me to ask, has this been only about the virus or something else?

Brian C. Joondeph, M.D., is a physician and writer. On Twitter as @retinaldoctor.

Editors Comment.

Having spent the past 30 years studying various plant extracts, including Quercetin, I have no doubt that this plant extract is the real deal.

The chart below shows the plants with the highest levels of Quercetin

The plants with the highest levels are Evening Primrose followed by May Apple, Goat weed, St Johnswort, and Black Tea.

The best way to extract these ethnobotanicals is by steeping them in hot water and drinking it cold. Just like you do when you make a cup of tea. (The weak tea in teabags will not be enough).

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  1. Does anyone know if this is available in New Zealand? (I love writing that name, it gives me huge pleasure). I know I need to get out more, but at this time its not so easy, could however be the easiest time, as draconian measures are supposed to be coming to New Zealand, boarder control Etc Etc. Reminds me of something? UMMMM what is it now let me think? Oh that is right Nazi Germany. East Germany during the lockup they had till the wall came down, and North Korea, China, North Vietnam during the crisis. All communist countries. Fcuk Jacinda Adern



  2. Quercetin is available in New Zealand but, strangely, most suppliers seem to be “out of stock” these days. I got a large bottle some months ago on the recommendation of Dr Zelenko who listed it as an alternative for HCQ in states such as New Zealand where it is effectively banned by our government who are not interested in public health only in the fat brown envelopes they receive from Big Pharma for pushing the deadly clot shot.



      • Can you advise your fellow commenters when the shipment from Iherb turns up. I loathe ordering anything direct from overseas as unlike Curious my experience indicates that 25% of orders are never despatched & what survives the trip usually doesn’t match the description.



        • nasska , we get our VitD from Iherb and like Curious I thought it was coming from the US , but I think NZ orders come from a company in Auckland which sells the same product and given Curious got his in 4 days I suspect it came the same way



            • Black Elderberry contains Quercetin


              Haven’t tried the above, but do take the following:



              You can literally hear the worms screaming when you get an urgent need to go #2. 😉

              An urgent need to go #2 with these products probably means you have squatters, so keep with the treatment

              I’m not a Doctor, so seek advice from a herbalist or natropath, or ring the product helplines. Both Nutralife and Malcolm Harker have 0800 numbers. These products are available everywhere including pharmacies.


              Getting rid of parasites is always a good thing to do on a regular basis. I’ve heard it said many time that 60% of human diseases are caused by parasites.

              And I’ve talked with Doctors and Pharmacists who spent time in Africa, and read many articles from the same professions in similar countries, and they all concur that treating patients for parasites is a big part of treating for disease. Even Ebola is carried by a parasite.

              It is also well known that heavy infestations of parasites have a very marked negative effect on ones persona. Even in NZ, most parents know that children become irritable when overdue for de-worming. At least it was in our generation.

              A case of multiple entities all battling for control of one body.

              I suspect that if the Level 3 Ardernites were put on a compulsory heavy course of these for a few weeks, it might diminish their hive mentality and snakey attitude, 😉

              Out of control parasitical infections are common amongst the sexually promiscuous especially those that insist on driving up clay tracks.



  3. sofosbuvir velpatasvir is utilized in the therapy of chronic hepatitis C infection disease. Sofosbuvir and Velpatasvir is a combination of two antiviral meds Sofosbuvir and Velpatasvir. They work by lowering the measure of the hepatitis C infection in the body and removing the infection from the blood throughout some undefined time frame.



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